Exemestane is an aromatase inhibitor drug used in bodybuilding to suppress the estrogenic side effects of steroids. It is also known under the name Aromasin, which was patented by Upjohn, the company that created it. The antiestrogen first appeared on the American market at the very beginning of the 2000s, immediately after receiving permission to sell.
Like other representatives of this class of antiestrogen, exemestane is actively used in medicine for the treatment of breast cancer in women during menopause. However, the drug has gained no less popularity in sports, as it is able to effectively suppress the estrogenic side effects of AAS. Its mechanism of action resembles the more popular aromatase inhibitors letrozole and anastrozole. However, unlike them, athletes often use exemestane in bodybuilding after a course of steroids.
Positive effects and properties of Exemestane
Exemestane is able to effectively block the aromatase enzyme, which is responsible for the process of converting testosterone into female hormones. As a result, the concentration of estrogen in the blood decreases. It is thanks to this that the drug is effective in the fight against breast cancer, since their development is directly related to an increase in estrogen levels. The same fact made exemestane popular among athletes who actively use steroids.
Many AAS have the ability to aromatize, and this leads to the development of certain side effects, such as fluid retention in the body and gynecomastia. The most serious negative effect among them is considered to be the second. However, with active fluid retention, blood pressure can increase significantly.
Numerous studies have shown that an increase in progesterone levels leads to the development of gynecomastia. Using exemestane in bodybuilding on a course of steroids, the athlete will be able to eliminate the risks of developing estrogenic side effects. Research has shown that Aromasin can reduce blood levels of estradiol by up to 85 percent of its baseline.
This is not the only positive property of the drug, which made it popular among builders. The fact is that taking exemestane in bodybuilding after a course of steroids can accelerate the secretion of endogenous male hormone. Some athletes do just that, including this aromatase inhibitor in their PCT. It should be recognized that letrozole and anastrozole also have a similar effect. They can send a signal to the pituitary gland about the need to start producing hormones of the gonadotropic group – luteinizing and follicle-stimulating.
Exemestane has some advantages over these drugs:
- has low androgenic activity;
- accelerates the secretion of insulin-like growth factor. Accelerates the secretion of insulin-like growth factor.
No other member of the aromatase inhibitor class has these properties. Using exemestane in bodybuilding after a course of steroids, an athlete can not only quickly restore the processes of testosterone synthesis, but due to an increase in the concentration of insulin-like growth factor, it shifts the balance between anabolism and catabolism towards the first.
Some builders are sure that this has a positive effect on the recovery of the body, because the rollback effect is minimized and muscle tissues are protected from destruction. However, if you look at the immediate results of using exemestane in bodybuilding after a course of steroids, it becomes clear that this is not desirable. Summing up the conversation about the positive effects of the drug, we highlight the most significant:
- an excellent remedy for the prevention of gynecomastia;
- effectively suppresses the level of female hormones;
- promotes the growth of the anabolic background;
- improves the relief of muscles;
- it is a good means of preventing hypertension;
- reduces the negative impact of estrogens on the work of the pituitary arch.
How exemestane works
When using the drug for medical purposes, it deprives cancer cells of the “feeding” of estrogens necessary for their vital activity. There is no doubt about the effectiveness of the use of Aromasin for these purposes. However, tamoxifen is recommended first. If this drug does not give positive results, you should start using exemestane.
However, we are more interested in the mechanisms of exemestane in relation to the suppression of the negative effects of anabolic steroids. Having become acquainted with the properties and effects of the drug, it is already possible to draw certain conclusions in this matter. It is important to remember that estrogen-type side effects may not occur when using steroids.
It is recommended to use exemestane in bodybuilding after a course of steroids. The drug can be most useful during the cycle of anabolic steroids, but not after its completion.
Instructions for use of Exemestane in bodybuilding
The recommended dosages of the drug are in the range from 12.5 to 25 milligrams, and it must be consumed every second day. However, in most cases, it is sufficient for athletes to use exemestane in an amount of 12.5 milligrams no more than three times a week.
If the maximum allowed dose is used, then the duration of such a course of exemestane should not be long. It is worth using 25 milligrams only if cholesterol is out of balance, and in other situations, limit yourself to the minimum dosage. Also in professional sports, exemestane is sometimes used one or two weeks before the start of the tournament, which allows you to improve muscle relief.